MEGATOMI.COM SECRETS

megatomi.com Secrets

megatomi.com Secrets

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Our new Obvious+ tissue clearing strategy is the sole technique that delipidates samples with no adjust in morphology and with minimum impact on structural integrity.

Megatome is a vibrating microtome meant to part a broad range of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome allows high-throughput tissue sectioning with uniform area profile, and also minimum tissue destruction and data loss.

Antibodies may well consider weeks to diffuse via only a few millimeters of tissue, using a steep labeling gradient from surface area to core.

Megatome is made for accuracy: the blade vibrates at a greater frequency and larger amplitude variety than other microtomes, and includes a special deflection Handle mechanism.

SE utilizes a rotational electric subject to disperse really electromobile molecules (like antibodies or surfactant micelles) throughout a porous sample without the need of harming electrically billed constructions inside the tissue. This enables two-four day clearing of intact organs,

Our preformulated EasyIndex Remedy raises and homogenize the refractive index of delipidated tissue samples, rendering them totally clear. This permits mild penetration in to the sample and makes sure the acquisition of significant-resolution, in-emphasis picture data.

Megatome is often a novel microtome that enables for top-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue damage and knowledge loss.

It’s the perfect time to update your microtome to Megatome. With accurate substantial-frequency slicing for an unmatched selection of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied programs.

The SmartSPIM light-weight sheet microscope gives unparalleled resolution and acquisition velocity during intact tissue volumes, though its modular design and style allows you to update and customise personal factors.

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Leverage the Distinct+ tissue clearing approach, in conjunction with eFLASH and patented stochastic electrotransport systems, to rapidly distinct and label complete organs. Critical highlights and options include:

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